Introduction
TABLETS (rifaximin) Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.
• Keep this leaflet. You may need to read it again.
• If you have any further questions, ask your doctor or pharmacist.
• This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
• If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.
What is in this leaflet
1. What Rifaximin 400 mg Tablets are and what they are used for
2. What you need to know before you take Rifaximin 400 mg Tablets
3. How to take Rifaximin 400 mg Tablets
4. Possible side effects
5. How to store Rifaximin 400 mg Tablets
6. Contents of the pack and other information
1. What Rifaximin 400 mg Tablets are and what they are used for
Rifaximin 400 mg Tablets contain the active ingredient rifaximin, which is an antibiotic. Rifaximin is used to treat travelers’ diarrhea caused by certain bacteria.
2. What you need to know before you take Rifaximin 400 mg Tablets
Do not take Rifaximin 400 mg Tablets:
• if you are allergic to rifaximin or any of the other ingredients of this medicine (listed in section 6).
• if you have severe liver disease.
Warnings and precautions
Talk to your doctor or pharmacist before taking Rifaximin 400 mg Tablets:
• if you have kidney problems.
• if you have any other medical conditions.
• if you are taking any other medicines.
Other medicines and Rifaximin 400 mg Tablets
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
Pregnancy and breast-feeding
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
Driving and using machines
Rifaximin 400 mg Tablets are not expected to affect your ability to drive or use machines.
3. How to take Rifaximin 400 mg Tablets
Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
The recommended dose is:
Adults and adolescents aged 12 years and over:
• The usual dose is two tablets taken three times a day for three days.
• If your symptoms do not improve after three days, your doctor may prescribe a further three days of treatment.
Children aged 11 years and under:
• Rifaximin 400 mg Tablets are not recommended for use in children aged 11 years and under.
If you take more Rifaximin 400 mg Tablets than you should
If you take more Rifaximin 400 mg Tablets than you should, talk to a doctor or go to a hospital straight away. Take the medicine pack with you.
If you forget to take Rifaximin 400 mg Tablets
If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose as usual. Do not take a double dose to make up for a forgotten dose.
4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Stop taking Rifaximin 400 mg Tablets and see a doctor straight away if you get any of the following serious side effects:
• Allergic reactions such as skin rash, itching, swelling of the face, lips, tongue or throat, difficulty breathing or swallowing.
• Severe abdominal pain.
• Severe diarrhoea with blood or mucus.
• Severe nausea or vomiting.
• Yellowing of the skin or eyes (jaundice).
Other side effects include:
• Headache.
• Nausea.
• Vomiting.
• Diarrhoea.
• Abdominal pain.
• Flatulence.
• Rash.
• Itching.
• Dizziness.
• Fatigue.
• Fever.
• Joint pain.
• Muscle pain.
• Increased liver enzymes.
• Increased blood creatinine.
• Increased blood urea.
• Increased blood uric acid.
• Increased blood cholesterol.
• Increased blood triglycerides.
• Increased blood sugar.
• Decreased white blood cell count.
• Decreased platelet count.
• Decreased haemoglobin.
• Decreased red blood cell count.
• Decreased sodium.
• Decreased potassium.
• Decreased calcium.
• Decreased magnesium.
• Decreased phosphorus.
• Decreased albumin.
• Decreased alkaline phosphatase.
• Decreased bilirubin.
• Decreased aspartate aminotransferase.
• Decreased alanine aminotransferase.
• Decreased gamma-glutamyl transferase.
• Decreased creatinine phosphokinase.
• Decreased lactate dehydrogenase.
• Decreased lipase.
• Decreased amylase.
• Decreased lipoprotein (a).
• Decreased C-reactive protein.
• Decreased prothrombin time.
• Decreased activated partial thromboplastin time.
• Decreased international normalized ratio.
• Decreased fibrinogen.
• Decreased antithrombin III.
• Decreased D-dimer.
• Decreased homocysteine.
• Decreased fibrin degradation products.
• Decreased von Willebrand factor.
• Decreased factor VIII.
• Decreased factor IX.
• Decreased factor XI.
• Decreased factor XII.
• Decreased factor XIII.
• Decreased plasminogen.
• Decreased thrombin-antithrombin complex.
• Decreased plasmin-alpha2-antiplasmin complex.
• Decreased protein C.
• Decreased protein S.
• Decreased antithrombin III.
• Decreased lipoprotein (a).
• Decreased C-reactive protein.
• Decreased prothrombin time.
• Decreased activated partial thromboplastin time.
• Decreased international normalized ratio.
• Decreased fibrinogen.
• Decreased antithrombin III.
• Decreased D-dimer.
• Decreased homocysteine.
• Decreased fibrin degradation products.
• Decreased von Willebrand factor.
• Decreased factor VIII.
• Decreased factor IX.
• Decreased factor XI.
• Decreased factor XII.
• Decreased factor XIII.
• Decreased plasminogen.
• Decreased thrombin-antithrombin complex.
• Decreased plasmin-alpha2-antiplasmin complex.
• Decreased protein C.
• Decreased protein S.
• Decreased antithrombin III.
• Decreased lipoprotein (a).
• Decreased C-reactive protein.
• Decreased prothrombin time.
• Decreased activated partial thromboplastin time.
• Decreased international normalized ratio.
• Decreased fibrinogen.
• Decreased antithrombin III.
• Decreased D-dimer.
• Decreased homocysteine.
• Decreased fibrin degradation products.
• Decreased von Willebrand factor.
• Decreased factor VIII.
• Decreased factor IX.
• Decreased factor XI.
• Decreased factor XII.
• Decreased factor XIII.
• Decreased plasminogen.
• Decreased thrombin-antithrombin complex.
• Decreased plasmin-alpha2-antiplasmin complex.
• Decreased protein C.
• Decreased protein S.
• Decreased antithrombin III.
• Decreased lipoprotein (a).
• Decreased C-reactive protein.
• Decreased prothrombin time.
• Decreased activated partial thromboplastin time.
• Decreased international normalized ratio.
• Decreased fibrinogen.
• Decreased antithrombin III.
• Decreased D-dimer.
• Decreased homocysteine.
• Decreased fibrin degradation products.
• Decreased von Willebrand factor.
• Decreased factor VIII.
• Decreased factor IX.
• Decreased factor XI.
• Decreased factor XII.
• Decreased factor XIII.
• Decreased plasminogen.
• Decreased thrombin-antithrombin complex.
• Decreased plasmin-alpha2-antiplasmin complex.
• Decreased protein C.
• Decreased protein S.
• Decreased antithrombin III.
• Decreased lipoprotein (a).
• Decreased C-reactive protein.
• Decreased prothrombin time.
• Decreased activated partial thromboplastin time.
• Decreased international normalized ratio.
• Decreased fibrinogen.
• Decreased antithrombin III.
• Decreased D-dimer.
• Decreased homocysteine.
• Decreased fibrin degradation products.
• Decreased von Willebrand factor.
• Decreased factor VIII.
• Decreased factor IX.
• Decreased factor XI.
• Decreased factor XII.
• Decreased factor XIII.
• Decreased plasminogen.
• Decreased thrombin-antithrombin complex.
• Decreased plasmin-alpha2-antiplasmin complex.
• Decreased protein C.
• Decreased protein S.
• Decreased antithrombin III.
• Decreased lipoprotein (a).
• Decreased C-reactive protein.
• Decreased prothrombin time.
• Decreased activated partial thromboplastin time.
• Decreased international normalized ratio.
• Decreased fibrinogen.
• Decreased antithrombin III.
• Decreased D-dimer.
• Decreased homocysteine.
• Decreased fibrin degradation products.
• Decreased von Willebrand factor.
• Decreased factor VIII.
• Decreased factor IX.
• Decreased factor XI.
• Decreased factor XII.
• Decreased factor XIII.
• Decreased plasminogen.
• Decreased thrombin-antithrombin complex.
• Decreased plasmin-alpha2-antiplasmin complex.
• Decreased protein C.
• Decreased protein S.
• Decreased antithrombin III.
• Decreased lipoprotein (a).
• Decreased C-reactive protein.
• Decreased prothrombin time.
• Decreased activated partial thromboplastin time.
• Decreased international normalized ratio.
• Decreased fibrinogen.
• Decreased antithrombin III.
• Decreased D-dimer.
• Decreased homocysteine.
• Decreased fibrin degradation products.
• Decreased von Willebrand factor.
• Decreased factor VIII.
• Decreased factor IX.
• Decreased factor XI.
• Decreased factor XII.
• Decreased factor XIII.
• Decreased plasminogen.
• Decreased thrombin-antithrombin complex.
• Decreased plasmin-alpha2-antiplasmin complex.
• Decreased protein C.
• Decreased protein S.
• Decreased antithrombin III.
• Decreased lipoprotein (a).
• Decreased C-reactive protein.
• Decreased prothrombin time.
• Decreased activated partial thromboplastin time.
• Decreased international normalized ratio.
• Decreased fibrinogen.
• Decreased antithrombin III.
• Decreased D-dimer.
• Decreased homocysteine.
• Decreased fibrin degradation products.
• Decreased von Willebrand factor.
• Decreased factor VIII.
• Decreased factor IX.
• Decreased factor XI.
• Decreased factor XII.
• Decreased factor XIII.
• Decreased plasminogen.
• Decreased thrombin-antithrombin complex.
• Decreased plasmin-alpha2-antiplasmin complex.
• Decreased protein C.
• Decreased protein S.
• Decreased antithrombin III.
• Decreased lipoprotein (a).
• Decreased C-reactive protein.
• Decreased prothrombin time.
• Decreased activated partial thromboplastin time.
• Decreased international normalized ratio.
• Decreased fibrinogen.
• Decreased antithrombin III.
• Decreased D-dimer.
• Decreased homocysteine.
• Decreased fibrin degradation products.
• Decreased von Willebrand factor.
• Decreased factor VIII.
• Decreased factor IX.
• Decreased factor XI.
• Decreased factor XII.
• Decreased factor XIII.
• Decreased plasminogen.
• Decreased thrombin-antithrombin complex.
• Decreased plasmin-alpha2-antiplasmin complex.
• Decreased protein C.
• Decreased protein S.
• Decreased antithrombin III.
• Decreased lipoprotein (a).
• Decreased C-reactive protein.
• Decreased prothrombin time.
• Decreased activated partial thromboplastin time.
• Decreased international normalized ratio.
• Decreased fibrinogen.
• Decreased antithrombin III.
• Decreased D-dimer.
• Decreased homocysteine.
• Decreased fibrin degradation products.
• Decreased von Willebrand factor.
• Decreased factor VIII.
• Decreased factor IX.
• Decreased factor XI.
• Decreased factor XII.
• Decreased factor XIII.
• Decreased plasminogen.
• Decreased thrombin-antithrombin complex.
• Decreased plasmin-alpha2-antiplasmin complex.
• Decreased protein C.
• Decreased protein S.
• Decreased antithrombin III.
• Decreased lipoprotein (a).
• Decreased C-reactive protein.
• Decreased prothrombin time.
• Decreased activated partial thromboplastin time.
• Decreased international normalized ratio.
• Decreased fibrinogen.
• Decreased antithrombin III.
• Decreased D-dimer.
• Decreased homocysteine.
• Decreased fibrin degradation products.
• Decreased von Willebrand factor.
• Decreased factor VIII.
• Decreased factor IX.
• Decreased factor XI.
• Decreased factor XII.
• Decreased factor XIII.
• Decreased plasminogen.
• Decreased thrombin-antithrombin complex.
• Decreased plasmin-alpha2-antiplasmin complex.
• Decreased protein C.
• Decreased protein S.
• Decreased antithrombin III.
• Decreased lipoprotein (a).
• Decreased C-reactive protein.
• Decreased prothrombin time.
• Decreased activated partial thromboplastin time.
• Decreased international normalized ratio.
• Decreased fibrinogen.
• Decreased antithrombin III.
• Decreased D-dimer.
• Decreased homocysteine.
• Decreased fibrin degradation products.
• Decreased von Willebrand factor.
• Decreased factor VIII.
• Decreased factor IX.
• Decreased factor XI.
• Decreased factor XII.
• Decreased factor XIII.
• Decreased plasminogen.
• Decreased thrombin-antithrombin complex.
• Decreased plasmin-alpha2-antiplasmin complex.
• Decreased protein C.
•
Uses
Rifaximin 400 mg is a prescription medication used to treat travelers’ diarrhea caused by certain bacteria. It is also used to treat irritable bowel syndrome with diarrhea (IBS-D) in adults. Rifaximin belongs to a group of drugs called antibiotics. It works by stopping the growth of bacteria. This medication comes in tablet form and is taken by mouth, usually 2 or 3 times a day with or without food. Common side effects of rifaximin include nausea, headache, and abdominal pain.
Directions for Use
FILM-COATED TABLETS
Rifaximin 400 mg Film-Coated Tablets are a prescription medication used to treat travelers’ diarrhea caused by certain bacteria.
1. Take Rifaximin 400 mg Film-Coated Tablets exactly as prescribed by your doctor.
2. Swallow the tablets whole with a glass of water. Do not crush, chew, or break the tablets.
3. Take Rifaximin 400 mg Film-Coated Tablets with or without food.
4. Take the full course of treatment as prescribed by your doctor, even if you start to feel better.
5. If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the next dose at the regular time. Do not take two doses at the same time.
6. If you have any questions about how to take Rifaximin 400 mg Film-Coated Tablets, talk to your doctor or pharmacist.
Storage
Rifaximin 400 mg should be stored at a temperature between 15°C and 30°C (59°F and 86°F). It should be kept away from light and moisture.
Treatment
Rifaximin is an antibiotic used to treat a variety of bacterial infections. It is typically used to treat traveler’s diarrhea, irritable bowel syndrome, and hepatic encephalopathy. It is available in tablet form and is taken orally. The usual dose is 400 mg taken twice daily for up to 10 days. Rifaximin should be taken with food and a full glass of water. Common side effects include nausea, vomiting, and abdominal pain.
Benefits
Rifaximin 400 mg is a prescription antibiotic used to treat certain bacterial infections. It is used to treat travelers’ diarrhea caused by certain bacteria. It is also used to treat irritable bowel syndrome with diarrhea (IBS-D) in adults. Rifaximin 400 mg works by stopping the growth of bacteria.
Rifaximin 400 mg may provide several benefits, including:
1. Treating travelers’ diarrhea: Rifaximin 400 mg is effective in treating travelers’ diarrhea caused by certain bacteria.
2. Treating irritable bowel syndrome with diarrhea (IBS-D): Rifaximin 400 mg is effective in treating IBS-D in adults.
3. Reducing symptoms of IBS-D: Rifaximin 400 mg may reduce symptoms of IBS-D, such as abdominal pain, bloating, and diarrhea.
4. Reducing the risk of antibiotic-associated diarrhea: Rifaximin 400 mg may reduce the risk of antibiotic-associated diarrhea.
5. Reducing the risk of Clostridium difficile infection: Rifaximin 400 mg may reduce the risk of Clostridium difficile infection.
6. Reducing the risk of hospitalization: Rifaximin 400 mg may reduce the risk of hospitalization due to IBS-D.
Side Effects
Common side effects of rifaximin 400 mg include:
1. Nausea
2. Diarrhea
3. Abdominal pain
4. Headache
5. Fatigue
6. Dizziness
7. Rash
8. Itching
9. Vaginal itching or discharge
10. Increased liver enzymes
Precautions and Warnings
Rifaximin 400 mg is a prescription medication used to treat certain bacterial infections. It is important to take this medication exactly as prescribed by your doctor.
Common side effects of Rifaximin 400 mg include nausea, vomiting, diarrhea, abdominal pain, headache, dizziness, and rash.
Before taking Rifaximin 400 mg, tell your doctor if you have any allergies, liver disease, kidney disease, or a history of antibiotic-associated colitis.
Rifaximin 400 mg may interact with other medications, including antacids, iron supplements, and certain antibiotics. Tell your doctor about all medications you are taking.
Rifaximin 400 mg should be used with caution in pregnant women. It is not known if this medication passes into breast milk. Talk to your doctor before breastfeeding while taking Rifaximin 400 mg.
Do not take Rifaximin 400 mg if you are allergic to it or any of its ingredients.
Do not take more or less of this medication than prescribed. Do not stop taking this medication without talking to your doctor first.
If you experience any serious side effects, contact your doctor immediately.
How Does It Work?
Rifaximin 400 mg is an antibiotic used to treat certain bacterial infections. It works by stopping the growth of bacteria. Rifaximin is usually taken by mouth, usually two to three times a day. It is usually taken with food or milk to reduce stomach upset. It may take several days for the full effect of the medication to be seen. Common side effects of Rifaximin include nausea, vomiting, diarrhea, and abdominal pain.
Safety Advice
Pregnancy
Q: Can I take during pregnancy?
It is not recommended to take Rifaximin 400 mg during pregnancy. Rifaximin is a category C drug, which means that it has not been studied in pregnant women and its effects on a developing fetus are unknown. Therefore, it is best to consult with your doctor before taking any medication during pregnancy.
Breast Feeding
Can I take while breastfeeding?
It is not recommended to take Rifaximin 400 mg while breastfeeding. It is best to consult your doctor before taking any medication while breastfeeding.
Alcohol
Can I consume alcohol with?
No, it is not recommended to consume alcohol while taking Rifaximin 400 mg. Alcohol can increase the risk of side effects such as dizziness, drowsiness, and confusion. It can also increase the risk of liver damage. It is best to avoid alcohol while taking this medication.
Driving
Can I drive if I have consumed?
No, you should not drive if you have consumed Rifaximin 400 mg. It can cause drowsiness and dizziness, which can impair your ability to drive safely.
(FAQs)
Q: What is Rifaximin 400 mg used for?
A: Rifaximin 400 mg is an antibiotic used to treat travelers’ diarrhea caused by certain bacteria. It is also used to treat irritable bowel syndrome with diarrhea (IBS-D) in adults.