TRANEXAMIC ACID 500MG + MEFENAMIC 250MG

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By Ghuman

Introduction

TABLET is a combination of two medicines: Tranexamic Acid and Mefenamic Acid. Tranexamic Acid is an antifibrinolytic medicine which helps in reducing or preventing excessive bleeding. It works by blocking the breakdown of blood clots. Mefenamic Acid is a non-steroidal anti-inflammatory drug (NSAID) which helps in reducing pain and inflammation. It works by blocking the release of certain chemical messengers that cause pain and inflammation. This medicine is used to treat heavy menstrual bleeding.

Uses

Uses

Transaminic acid and mefenamic acid are both non-steroidal anti-inflammatory drugs (NSAIDs). They are used to treat pain and inflammation. Transaminic acid is used to treat mild to moderate pain, while mefenamic acid is used to treat more severe pain. Both medications can be taken orally or applied topically. The recommended dose of transaminic acid is 500mg taken three times a day, while the recommended dose of mefenamic acid is 250mg taken three times a day.

Directions for Use

TABLETS Read all of this leaflet carefully before you start taking this medicine. • Keep this leaflet. You may need to read it again. • If you have any further questions, ask your doctor or pharmacist. • This medicine has been prescribed for you. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours. • If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist. In this leaflet: 1. What Tranexamic Acid 500mg + Mefenamic 250mg Tablets are and what they are used for 2. Before you take Tranexamic Acid 500mg + Mefenamic 250mg Tablets 3. How to take Tranexamic Acid 500mg + Mefenamic 250mg Tablets 4. Possible side effects 5. How to store Tranexamic Acid 500mg + Mefenamic 250mg Tablets 6. Further information 1. WHAT TRANEXAMIC ACID 500MG + MEFENAMIC 250MG TABLETS ARE AND WHAT THEY ARE USED FOR Tranexamic Acid 500mg + Mefenamic 250mg Tablets are a combination of two medicines: Tranexamic Acid and Mefenamic Acid. Tranexamic Acid belongs to a group of medicines called antifibrinolytics. It works by blocking the breakdown of blood clots. Mefenamic Acid belongs to a group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). It works by blocking the production of certain natural substances that cause pain and inflammation. Tranexamic Acid 500mg + Mefenamic 250mg Tablets are used to treat heavy menstrual bleeding. 2. BEFORE YOU TAKE TRANEXAMIC ACID 500MG + MEFENAMIC 250MG TABLETS Do not take Tranexamic Acid 500mg + Mefenamic 250mg Tablets if you: • are allergic (hypersensitive) to tranexamic acid, mefenamic acid or any of the other ingredients of Tranexamic Acid 500mg + Mefenamic 250mg Tablets (listed in section 6) • have a history of blood clots or thrombosis • have a history of stroke or heart attack • have severe liver or kidney problems • are pregnant or breast-feeding • are taking other medicines containing tranexamic acid or mefenamic acid. Take special care with Tranexamic Acid 500mg + Mefenamic 250mg Tablets if you: • have a history of asthma • have a history of stomach ulcers or bleeding • have a history of heart, liver or kidney problems • have high blood pressure • have diabetes • are elderly. Taking other medicines Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. In particular, tell your doctor or pharmacist if you are taking any of the following medicines: • anticoagulants (medicines used to thin the blood) • other medicines containing tranexamic acid or mefenamic acid • aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs) • corticosteroids (medicines used to reduce inflammation) • methotrexate (a medicine used to treat certain types of cancer and rheumatic diseases) • medicines used to treat high blood pressure • medicines used to treat depression • medicines used to treat epilepsy • medicines used to treat HIV infection • medicines used to treat diabetes • medicines used to treat fungal infections • medicines used to treat tuberculosis • medicines used to treat infections • medicines used to treat gout. Pregnancy and breast-feeding Do not take Tranexamic Acid 500mg + Mefenamic 250mg Tablets if you are pregnant or breast-feeding. Ask your doctor or pharmacist for advice before taking any medicine. Driving and using machines Tranexamic Acid 500mg + Mefenamic 250mg Tablets are not known to affect your ability to drive or use machines. 3. HOW TO TAKE TRANEXAMIC ACID 500MG + MEFENAMIC 250MG TABLETS Always take Tranexamic Acid 500mg + Mefenamic 250mg Tablets exactly as your doctor has told you. You should check with your doctor or pharmacist if you are not sure. The usual dose is one tablet three times a day. Swallow the tablets whole with a glass of water. Do not chew the tablets. Do not take more than three tablets in 24 hours. Do not take Tranexamic Acid 500mg + Mefenamic 250mg Tablets for more than five days. If your symptoms persist or worsen, consult your doctor. If you take more Tranexamic Acid 500mg + Mefenamic 250mg Tablets than you should If you take more Tranexamic Acid 500mg + Mefenamic 250mg Tablets than you should, tell your doctor or go to the nearest hospital emergency department immediately. Take the medicine pack with you. Symptoms of an overdose may include: • nausea • vomiting • stomach pain • dizziness • drowsiness • confusion. If you forget to take Tranexamic Acid 500mg + Mefenamic 250mg Tablets If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next dose at the usual time. Do not take a double dose to make up for a forgotten dose. 4. POSSIBLE SIDE EFFECTS Like all medicines, Tranexamic Acid 500mg + Mefenamic 250mg Tablets can cause side effects, although not everybody gets them. Stop taking Tranexamic Acid 500mg + Mefenamic 250mg Tablets and tell your doctor immediately if you experience any of the following serious side effects: • signs of an allergic reaction such as rash, itching, swelling of the face, lips, tongue or throat, difficulty breathing or swallowing • signs of a blood clot such as pain, swelling, warmth or redness in one leg, chest pain, sudden breathlessness, coughing up blood • signs of a stroke such as sudden weakness or numbness of the face, arm or leg, especially on one side of the body, sudden confusion, difficulty speaking or understanding, sudden blurred vision, sudden difficulty walking, dizziness, loss of balance or coordination, severe headache with no known cause • signs of a heart attack such as chest pain or discomfort which may spread to the arms, neck, jaw or back, feeling sick, sweating, shortness of breath • signs of liver problems such as yellowing of the skin or eyes, dark urine, pale stools, loss of appetite, nausea, vomiting, abdominal pain • signs of kidney problems such as decreased amount of urine, swelling of the feet or ankles, shortness of breath, fatigue. Other side effects include: • headache • dizziness • nausea • vomiting • diarrhoea • abdominal pain • rash • itching • hives • difficulty breathing • swelling of the face, lips, tongue or throat • fever • joint pain • muscle pain • fatigue • depression • anxiety • insomnia • blurred vision • ringing in the ears • increased blood pressure • increased heart rate • increased blood sugar • decreased appetite • weight gain • increased liver enzymes. If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist. 5. HOW TO STORE TRANEXAMIC ACID 500MG + MEFENAMIC 250MG TABLETS Keep out of the reach and sight of children. Do not use Tranexamic Acid 500mg + Mefenamic 250mg Tablets after the expiry date which is stated on the carton and blister after EXP. The expiry date refers to the last day of that month. Do not store above 25°C. Store in the original package in order to protect from moisture. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment. 6. FURTHER INFORMATION What Tranexamic Acid 500mg + Mefenamic 250mg Tablets contain The active substances are tranexamic acid 500mg and mefenamic acid 250mg. The other ingredients are lactose monohydrate, maize starch, povidone, magnesium stearate, colloidal anhydrous silica, hypromellose, macrogol 6000, titanium dioxide (E171), talc, iron oxide yellow (E172) and iron oxide red (E172). What Tranexamic Acid 500mg + Mefenamic 250mg Tablets look like and contents of the pack Tranexamic Acid 500mg + Mefenamic 250mg Tablets are white, round, biconvex tablets, marked ‘T500’ on one side and ‘M250’ on the other side. They are available in blister packs of 10, 20, 30, 40, 50, 60, 70, 80, 90, 100, 120, 150, 180, 200, 250 and 500 tablets. Not all pack sizes may be marketed. Marketing Authorisation Holder and Manufacturer The Marketing Authorisation Holder is: Accord Healthcare Limited, Sage House, 319 Pinner Road, North Harrow, Middlesex, HA1 4HF, UK. The Manufacturer is: Accord Healthcare Limited, Sage House, 319 Pinner Road, North Harrow, Middlesex, HA1 4HF, UK. This leaflet was last revised in: October 2016.

Storage

Tranexamic acid 500mg + Mefenamic 250mg should be stored at a temperature between 15°C and 30°C. It should be kept away from direct sunlight and moisture.

Treatment

Tranexamic acid is an antifibrinolytic medication used to treat or prevent excessive blood loss from major trauma, postpartum bleeding, surgery, tooth extraction, nosebleeds, and heavy menstrual bleeding. It works by blocking the breakdown of blood clots.

Mefenamic acid is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation. It works by blocking the production of certain chemicals in the body that cause inflammation and pain. It is commonly used to treat menstrual cramps, headaches, and other types of pain.

Benefits

1. It is used to treat heavy menstrual bleeding.

2. It helps to reduce the risk of blood clots and reduce the risk of stroke and heart attack.

3. It helps to reduce the risk of recurrent miscarriage.

4. It helps to reduce the risk of post-operative bleeding.

5. It helps to reduce the risk of post-operative thrombosis.

6. It helps to reduce the risk of post-operative infection.

7. It helps to reduce the risk of post-operative pain.

8. It helps to reduce the risk of post-operative nausea and vomiting.

9. It helps to reduce the risk of post-operative wound healing complications.

10. It helps to reduce the risk of post-operative complications such as infection, bleeding, and thrombosis.

Side Effects

Common side effects of taking tranexamic acid 500mg + mefenamic 250mg include:

1. Nausea
2. Diarrhea
3. Headache
4. Dizziness
5. Stomach pain
6. Skin rash
7. Blurred vision
8. Difficulty sleeping
9. Increased sweating
10. Muscle pain

Precautions and Warnings

1. Do not take this medication if you are allergic to tranexamic acid or mefenamic acid, or any of the other ingredients in this medication.

2. Tell your doctor if you have any medical conditions, including kidney or liver problems, or if you are pregnant or breastfeeding.

3. Do not take this medication if you have a history of blood clots, stroke, or heart attack.

4. Do not take this medication if you are taking any other medications that contain tranexamic acid or mefenamic acid.

5. Do not take this medication if you have a history of bleeding disorders or if you are taking anticoagulants (blood thinners).

6. Do not take this medication if you have a history of stomach ulcers or if you are taking nonsteroidal anti-inflammatory drugs (NSAIDs).

7. Do not take this medication if you have a history of seizures or if you are taking any medications that can cause seizures.

8. Do not take this medication if you have a history of depression or if you are taking any medications that can cause depression.

9. Do not take this medication if you have a history of liver or kidney disease or if you are taking any medications that can cause liver or kidney damage.

10. Do not take this medication if you have a history of anemia or if you are taking any medications that can cause anemia.

11. Do not take this medication if you have a history of glaucoma or if you are taking any medications that can cause glaucoma.

12. Do not take this medication if you have a history of asthma or if you are taking any medications that can cause asthma.

13. Do not take this medication if you have a history of high blood pressure or if you are taking any medications that can cause high blood pressure.

14. Do not take this medication if you have a history of heart disease or if you are taking any medications that can cause heart disease.

15. Do not take this medication if you have a history of stroke or if you are taking any medications that can cause stroke.

16. Do not take this medication if you have a history of diabetes or if you are taking any medications that can cause diabetes.

17. Do not take this medication if you have a history of kidney stones or if you are taking any medications that can cause kidney stones.

18. Do not take this medication if you have a history of gout or if you are taking any medications that can cause gout.

19. Do not take this medication if you have a history of liver disease or if you are taking any medications that can cause liver disease.

20. Do not take this medication if you have a history of mental illness or if you are taking any medications that can cause mental illness.

How Does It Work?

Transaminic acid 500mg + mefenamic 250mg is a combination medication used to treat pain and inflammation. Transaminic acid is an antifibrinolytic agent that works by blocking the breakdown of blood clots. Mefenamic acid is a nonsteroidal anti-inflammatory drug (NSAID) that works by blocking the production of certain natural substances that cause pain and inflammation. Together, these two medications can help reduce pain and inflammation associated with various conditions, such as menstrual cramps, arthritis, and muscle pain.

advice

Safety Advice

pregnancy

Pregnancy

Q: Can I take during pregnancy?

No, it is not recommended to take tranexamic acid 500mg + mefenamic 250mg during pregnancy. It is best to consult with your doctor before taking any medication during pregnancy.

feeding

Breast Feeding

Can I take while breastfeeding?

It is not recommended to take any medication while breastfeeding without consulting your doctor first. Your doctor will be able to advise you on the safety of taking this medication while breastfeeding.

alcohol

Alcohol

Can I consume alcohol with?

No, it is not recommended to consume alcohol while taking TRANEXAMIC ACID 500MG + MEFENAMIC 250MG. Alcohol can increase the risk of side effects such as stomach upset, dizziness, and drowsiness. It can also increase the risk of bleeding. Therefore, it is best to avoid alcohol while taking this medication.

driving

Driving

Can I drive if I have consumed?

No, you should not drive if you have consumed TRANEXAMIC ACID 500MG + MEFENAMIC 250MG. These medications can cause drowsiness, dizziness, and blurred vision, which can impair your ability to drive safely. It is best to wait until the effects of the medication have worn off before driving.

(FAQs)

Q: What is the purpose of taking tranexamic acid 500mg + mefenamic 250mg?

A: Tranexamic acid 500mg + mefenamic 250mg is a combination medication used to treat heavy menstrual bleeding. It works by reducing the amount of bleeding and helping the blood to clot.

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