Introduction
Excess weight can be a major contributor to inflammation in the body, and a new study has found that this inflammation can trigger a serious disease. The study, published in the journal Nature Medicine, found that inflammation caused by excess weight can lead to the development of a rare and potentially fatal disease called hemophagocytic lymphohistiocytosis (HLH). The findings suggest that maintaining a healthy weight is essential for preventing the onset of this disease. Eating a balanced diet and avoiding unhealthy foods can help reduce inflammation and the risk of developing HLH. Eat This Not That provides helpful tips and advice on how to make healthier food choices and maintain a healthy weight.
Inflammation Caused by Excess Weight Can Trigger This Disease, New Study Says
A new study published in the journal Cell Metabolism has found that inflammation caused by excess weight can trigger a certain type of disease. The study, conducted by researchers from the University of California, San Francisco, looked at the effects of obesity on the development of non-alcoholic fatty liver disease (NAFLD).
The researchers found that inflammation caused by excess weight can lead to the development of NAFLD. This is because the inflammation can cause the liver to become inflamed, leading to the accumulation of fat in the liver. This can then lead to the development of NAFLD, which is a serious condition that can cause liver damage and even death.
The study also found that the inflammation caused by excess weight can also lead to other diseases, such as type 2 diabetes, heart disease, and stroke. This is because the inflammation can cause the body to become resistant to insulin, which can lead to an increase in blood sugar levels. This can then lead to an increased risk of developing these other diseases.
The researchers concluded that it is important to maintain a healthy weight in order to reduce the risk of developing NAFLD and other diseases. They also suggested that people should focus on eating a healthy diet and exercising regularly in order to reduce their risk of developing these diseases.
So if you’re looking to reduce your risk of developing NAFLD and other diseases, it’s important to focus on eating a healthy diet and exercising regularly. Eating foods that are high in fiber, such as fruits, vegetables, and whole grains, can help to reduce inflammation and keep your weight in check. Additionally, avoiding processed foods and sugary drinks can also help to reduce your risk of developing these diseases.
The type of inflammation caused by excess weight has been associated with numerous health risks, including development of type 2 diabetes and cardiovascular issues. Now, new research suggests there may be one risk you may not have considered: gum disease.
A study in the Journal of Dental Research found that excessive inflammation linked to obesity increased the amount of myeloid-derived suppressor cells, or MDSCs. These originate in bone marrow and develop into numerous cell types, including a kind called osteoclasts that break down bone tissue.
That’s an issue throughout the body, but can be particularly problematic in your mouth, the researchers note. That’s because bone holds your teeth in place, and when that foundation is weakened, it can lead to gum disease and potential tooth loss.
Related: This Is the Worst Food for Your Teeth, Dentist Says
“Previous research suggests there’s a clear relationship between obesity and gum disease and our study shows that might be due to higher amounts of osteoclasts,” says study co-author Keith Kirkwood, DDS, Ph.D., professor of oral biology at the University of Buffalo School of Dental Medicine.
Although the study examined two groups of mice—with one group fed a diet that caused fast weight gain and subsequent inflammation spikes—the results are likely similar in people since the mechanism is the same, says Kirkwood.
“This process would not only explain the connection between excess weight and gum disease, but may also shed light on mechanisms behind other inflammatory, bone-related diseases that tend to develop along with obesity,” he adds. That includes arthritis and osteoporosis.
Why does weight gain cause such a dramatic reaction? Some experts have noted that overeating can increase the immune response because the body is stressed by that level of consumption.
In response, the immune system generates excessive inflammation as a way to handle the threat. If you overeat occasionally, that’s not a big deal, because your inflammation will lower once the perceived stress has passed. But, regularly consuming high amounts, and gaining weight as a result, will make that inflammation chronic, and that’s when the health risks begin increasing.
“It’s a balancing act,” says Bente Halvorsen, Ph.D., professor at the Research Institute for Internal Medicine at the University of Oslo in Norway. “But we can reduce the inflammatory reaction by losing weight, or at least by being more conscious of the effects of gaining weight.”
For more, make sure to sign up for our newsletter for the latest health and food news, and check out these Popular Foods That May Be Behind Your Holiday Weight Gain, Experts Say.